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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIK2
All Species:
17.88
Human Site:
Y733
Identified Species:
35.76
UniProt:
Q9H0K1
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0K1
NP_056006.1
926
103915
Y733
K
Q
S
Q
L
Q
A
Y
F
N
Q
M
Q
I
A
Chimpanzee
Pan troglodytes
XP_508750
883
99166
Y690
K
Q
S
Q
L
Q
A
Y
F
N
Q
M
Q
I
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546528
993
110460
Y807
K
Q
S
Q
L
Q
A
Y
F
N
Q
M
Q
I
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFH6
931
104180
Y733
K
Q
S
Q
L
Q
A
Y
F
N
Q
M
Q
I
A
Rat
Rattus norvegicus
Q9R1U5
776
84890
G603
A
R
T
K
G
F
L
G
L
N
K
I
K
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511894
801
88312
R629
P
A
P
A
R
P
P
R
S
I
P
P
A
F
H
Chicken
Gallus gallus
Q9IA88
798
88848
S626
R
A
A
R
S
A
M
S
P
F
Q
H
A
Q
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
E965
Q
Q
L
G
Q
A
A
E
S
L
D
S
A
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569972
1398
149888
T1183
P
P
P
P
G
L
Y
T
H
H
Q
L
G
V
G
Honey Bee
Apis mellifera
XP_397175
718
80391
R546
I
Q
D
S
G
K
A
R
G
H
L
D
L
V
H
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
T983
R
N
T
R
N
R
Q
T
F
H
G
K
T
E
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
S340
D
N
R
F
R
V
P
S
G
Y
L
E
S
E
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.2
N.A.
84.7
N.A.
90.8
43.2
N.A.
45.2
45.4
N.A.
31.5
N.A.
29.6
37.4
23.8
N.A.
Protein Similarity:
100
95.3
N.A.
87.5
N.A.
94.4
56.7
N.A.
58.6
58.9
N.A.
45.2
N.A.
40
49.3
38.1
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
6.6
N.A.
0
6.6
N.A.
13.3
N.A.
6.6
13.3
6.6
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
46.6
N.A.
0
26.6
N.A.
20
N.A.
26.6
33.3
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
9
9
0
17
50
0
0
0
0
0
25
0
34
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
0
0
0
0
0
0
0
9
9
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
9
0
0
0
9
0
17
0
% E
% Phe:
0
0
0
9
0
9
0
0
42
9
0
0
0
9
9
% F
% Gly:
0
0
0
9
25
0
0
9
17
0
9
0
9
9
9
% G
% His:
0
0
0
0
0
0
0
0
9
25
0
9
0
0
17
% H
% Ile:
9
0
0
0
0
0
0
0
0
9
0
9
0
34
0
% I
% Lys:
34
0
0
9
0
9
0
0
0
0
9
9
9
0
9
% K
% Leu:
0
0
9
0
34
9
9
0
9
9
17
9
9
0
9
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
34
0
0
0
% M
% Asn:
0
17
0
0
9
0
0
0
0
42
0
0
0
0
0
% N
% Pro:
17
9
17
9
0
9
17
0
9
0
9
9
0
9
17
% P
% Gln:
9
50
0
34
9
34
9
0
0
0
50
0
34
9
0
% Q
% Arg:
17
9
9
17
17
9
0
17
0
0
0
0
0
0
0
% R
% Ser:
0
0
34
9
9
0
0
17
17
0
0
9
9
0
0
% S
% Thr:
0
0
17
0
0
0
0
17
0
0
0
0
9
0
0
% T
% Val:
0
0
0
0
0
9
0
0
0
0
0
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
34
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _